05-Dec-2023 - Charcot-Marie-Tooth disease type 2A: identification of a potential therapeutic approach

A recent study conducted by researchers from the “Centro Dino Ferrari”, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, and accepted for online [...]

17-Jul-2023 - The project MAINSTREAM

Primary Progressive Aphasia (PPA) is a group of neurodegenerative disorders that primarily affects language and is characterized as a progressive decline in expressing wants and [...]

29-Mar-2023 - Duchenne Muscular Distrophy: the importance of microbiota as a potential target for therapeutic interventions

Duchenne muscular dystrophy (DMD) is a progressive severe muscle-wasting disease caused by mutations in DMD gene, encoding dystrophin, that leads to loss of muscle function [...]

07-Nov-2022 - SMA Project: scientific activity and dissemination

https://youtu.be/iyQidcfYd0c   One of the main goal of Research supported by Fondazione Cariplo involves the interaction between science world and civil society. Our project embraces a well-defined and detailed dissemination [...]

11-May-2022 - CMT2A: identification of a novel patogenic mutation in the MFN2 gene in a cohort of patients with Charcot-Marie-Tooth type 2 A

A recent study characterized at a clinical and genetic level a cohort of 13-patients diagnosed with Charcot-Marie-Tooth di tipo 2A (CMT2A). This study has been [...]

13-Dec-2021 - SMARD1: aperto uno studio clinico di terapia genica presso il Nationwide Children’s Hospital di Columbus (USA)

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10-Dec-2021 - Al Prof. Giacomo Pietro Comi il titolo di Presidente dell’Associazione Italiana di Miologia

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09-Dec-2021 - SLA, un imponente studio internazionale, col contributo italiano, identifica nuovi geni responsabili della patologia definendo i meccanismi patogenetici e l’esordio motoneuronale della malattia

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01-Dec-2021 - SMA: I peptidi “alleati” per migliorare l’efficacia della terapia

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22-Nov-2021 - Premiata la ricercatrice Chiara Villa per l’avanzamento nella ricerca sulle nanoparticelle quale nuovo approccio nel trattamento dell’Atassia di Friedreich

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13-Oct-2021 - A Yvan Torrente il riconoscimento “Neurologist of the Year 2021”

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04-Oct-2021 - Alzheimer: mutazioni di NPC1 e NPC2 possono essere un fattore di rischio per lo sviluppo della malattia

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28-Sep-2021 - Demenze neurodegenerative: la “catena leggera dei neurofilamenti” è un nuovo potenziale strumento di diagnosi precoce

22-Sep-2021 - Atrofia muscolare spinale, prima somministrazione della terapia genica come farmaco innovativo al Policlinico di Milano

17-Sep-2021 - Seconda conferenza MSA virtuale per tutta la comunità

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10-Sep-2021 - 15 settembre 2021
GIORNATA INTERNAZIONALE DELLE DISTROFIE MIOTONICHE

  SCARICA, COMPILA E INVIA IL MODULO DI ADESIONE: Scheda iscrizione_15.09.2021 Malattie Miotoniche   RICORDIAMO CHE LA PARTECIPAZIONE E’ RISERVATA A MEDICI DI MEDICINA GENERALE […]

26-Aug-2021 - Atassia di Friedreich – Scoperte nanoparticelle che rallentano l’avanzare della malattia

Lo studio, coordinato dell’Università Statale di Milano e dal Policlinico di Milano, assieme all’Università di Milano-Bicocca, all’Università di Torino e all’ University of Miami Miller [...]

20-Aug-2021 - Il processo di sumoilazione è importante per il corretto assemblaggio e funzionamento del complesso SMN e rappresenta un nuovo bersaglio terapeutico per l’Atrofia Muscolare Spinale (SMA)

L'atrofia muscolare spinale (SMA) è una malattia neuromuscolare progressiva causata da mutazioni nel gene della sopravvivenza motoneuronale 1 (SMN1), a cui conseguono bassi livelli di [...]

06-May-2021 - Impairment of the neurotrophic signaling hub B-Raf contributes to motoneuron degeneration in Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA) is a fatal neurodegenerative disease caused by mutations in the Survival of Motoneuron 1 gene (SMN1) that results in low SMN [...]

10-Nov-2020 - Study of neuron-astrocyte interaction using multi-modal integrated bioinformatics workflow identifies a new potential therapeutic target for ALS

Death receptor-6 (DR6) on motor neuron was identified as possible disease modifier of Amyotrophic Lateral Sclerosis by the researchers of the Centro Dino Ferrari, University […]

17-Sep-2020 - New therapies and systemic impact of Spinal Muscular Atrophy

Our team from the Dino Ferrari Center of the University of Milan discusses the advancements and challenges of new therapies for patients with Spinal Muscular […]

19-May-2020 - Amyotrophic Lateral Sclerosis: the role of a miRNA identified as a possible therapeutic target

A recent study published on the international journal Progress in neurobiology and carried out by the research group (Dr. Monica Nizzardo and Dr. Mafalda Rizzuti) […]

17-Mar-2020 - SMARD1 Natural History Study at Centro Dino Ferrari Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico

Spinal muscular atrophy with respiratory distress type 1 (SMARD 1)is a rare, autosomal recessive neuromuscular disease characterized by degeneration of the motor neuron that manifests […]

25-Feb-2020 - A recent study investigated potential treatment biomarkers of spinal muscular atrophy (SMA) type 3

A recent study published on the Journal of Cellular and Clinical Medicine and conducted by the researchers of the Centro Dino Ferrari, University of Milan, […]

18-Feb-2020 - ALS and SMA: study of molecular mechanisms in resistant neurons identifies a new potential therapeutic target

SYT13 is an oculomotor restricted gene, identified as possible disease modifier of Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy (SMA), by the researchers of the […]

05-Feb-2019 - Spinal Muscular Atrophy: from the study of molecular mechanisms to the identification of new therapeutic targets

Terapia per Atrofia Muscolare Spinale: uno studio recente ha permesso di individuare nuovi bersagli terapeutici per la SMA. Scopri di più…

29-Mar-2018 - [:it]Il commissario europeo per la salute e la sicurezza alimentare, Vytenis Andriukaitis, in visita al nostro ospedale

Oggi 1 dicembre presso il Policlinico di Milano, si svolgerà l’incontro scientifico tra i nostri ricercatori e quelli della Columbia University e Atene…

19-Dec-2017 - The loss of macular ganglion cells begins from the early stages of disease and correlates with brain atrophy in multiple sclerosis patients

  Mutations in the vesicular trafficking protein annexin A11 are associated with Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. We […]

19-Dec-2017 - CSF β-amyloid and white matter damage: a new perspective on Alzheimer’s disease

  Mutations in the vesicular trafficking protein annexin A11 are associated with Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. We […]

01-Dec-2017 - 7PQ project (update 2017)

Oggi 1 dicembre presso il Policlinico di Milano, si svolgerà l’incontro scientifico tra i nostri ricercatori e quelli della Columbia University e Atene…

29-Nov-2017 - [:it]Reclutamento pazienti adulti affetti da Distrofia Muscolare di Becker per nuovo trial terapeutico

Italfarmaco ha lanciato una sperimentazione di fase II in pazienti affetti da Distrofia Muscolare di Becker, forma che seppur più lieve rispetto alla DMD ne condivide i principali meccanismi patogenetici …

24-Nov-2017 - [:it]Seminario: Stimolazione Cerebrale Profonda e Malattia di Parkinson

Il Dottor Alessio Di Fonzo, responsabile del Laboratorio Malattia di Parkinson e disordini del Movimento del “Centro Dino Ferrari” con la sua equipe terranno un seminario …

21-Nov-2017 - [:it]Cellule staminali del cervello: nuova scoperta italiana

La risonanza magnetica svela l’impronta digitale metabolica delle cellule staminali cerebrali: una strada per la corretta diagnosi e per la terapia mirata con staminali nelle malattie neurodegenerative…

20-Nov-2017 - [:it]Seminario Dr. Fabian Feiguin, PhD International Center for Genet

Il rinomato Dr. Fabian Feiguin dell’ International Center for Genetic Engineering and Biotechnology (ICGEB) di Trieste terrà un Seminario presso Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico 22 Novembre 2017 …

31-Jul-2017 - [:it]Charcot-Marie-Tooth di tipo 2A: a che punto è la ricerca sulla terapia genica

Il progetto sulla malattia rara Charcot-Marie-Tooth di tipo 2A, è sotto la responsabilità scientifica della Prof.ssa Stefania Corti, del Prof. Giacomo Pietro Comi e del Prof. Nereo Bresolin, del “Centro Dino Ferrari” e sostenuto dall’Associazione Progetto Mitofusina2 onlus …

05-May-2017 - Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

  Mutations in the vesicular trafficking protein annexin A11 are associated with Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. We […]

04-Apr-2017 - An important step against SLA

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis Homing in on poly(GP) proteins A mutation in the C9ORF72 gene causes amyotrophic […]

30-Jun-2016 - Cladribine in Multiple Sclerosis: Overview

15-Jun-2016 - JUN 20 -“Unraveling multiple sclerosis heterogeneity”

25-Feb-2016 - Antisense oligonucleotides Morpholino therapy rescues ALS pathological effects in human and murine ALS models15

Antisense oligonucleotides Morpholino therapy rescues ALS pathological effects in human and murine ALS models15 M.Nizzardo, C. Simone, F. Rizzo, G. Ulzi, A. Ramirez, M. Rizzuti, […]

22-Feb-2016 - NEW PERSPECTIVES IN THE ONSET OF DMD DURING FETAL MUSCLE DEVELOPMENT

Research Article published on dec 2015   Andrea Farini, Clementina Sitzia, Letizia Cassinelli, Federica Colleoni, Daniele Parolini, Umberto Giovanella, Simona Maciotta, Augusto Colombo, Mirella Meregalli, […]

14-Dec-2015 - PRECLINICAL TESTING OF A TRANSLOCATOR PROTEIN LIGAND FOR THE TRATEMENTO OF ALS

SCIENTIFIC MEETING 4 p.m. DECEMBER 16th, 2015 ROOM 1 – PAVILION MONTEGGIA OSPEDALE MAGGIORE POLICLINICO

20-Nov-2015 - Histologic muscular history in steroid-treated and untreated patients with Duchenne dystrophy.

 Histologic muscular history in steroid-treated and untreated patients with Duchenne dystrophy OBJECTIVE: Duchenne muscular dystrophy (DMD) is a lethal disease. The outcome measures used in […]

18-Nov-2015 - 23 nov 2015 – NO-MND Day

15-Jul-2015 - 7PQ NO-MND Seminar

05-May-2015 - DAMNDPATHS PROJECT

17-Apr-2015 - Impaired Muscle Mitochondrial Biogenesis and Myogenesis in Spinal Muscular Atrophy

Article Published on Jama Neurology, 6th april 2015. The Neuromuscular and Rare Diseases Unit directed by Dr Maurizio Moggio, in collabroation with the Laboratory of […]

17-Apr-2015 - American Academy of Neurology a Washington D.C

 On 22nd april during the annual meeting of American Academy of Neurology a Washington D.C Dr. Corti will take a speech titled: “AAV9-mediated Gene Therapy […]

16-Mar-2015 - Gene Therapy Reverses Effects of SMARD1 in a mouse model

Gene Therapy Reverses Effects of SMARD1 in a mouse model A study conducted by Centro Dino Ferrari, Università degli Studi di Milano and IRCCS Fondazione Ca’ […]

13-Jan-2015 - 15/1/15 Gene therapy and clinical trials for Muscular Dystrophies at Nationwide Children’s Hospital

19-Sep-2014 - 22nd september 14 -” Visual rating of Frontal Lobe Atrophy “

05-Sep-2014 - “Clinical Challenge: A case of hemichorea / ballism with frontal behavioural disturbance”

Mario Masellis, M.Sc. (Pharm), MD, PhD, FRCPC Sunnybrook Health Sciences Centre, Toronto, Canada   Wednesday September 10 Ospedale Maggiore Policlinio Aula 1, Pad. Monteggia Time […]

05-Sep-2014 - “MiR 223 regulates Myeloid Suppressor Cells during EAE “

Monday  September 8th Ospedale Maggiore Policlinico Aula 1, Pad. Monteggia Time  2.30 pm  

19-Mar-2014 - Donate your 5×1000 to scientific research of “Centro Dino Ferrari”

press 14

18-Feb-2014 - First International Conference on Mitofusin 2

volantino CONVEGNO ing

16-Jan-2014 - Mitochondrial Fusion Proteins and Human Diseases

Michela Ranieri,1 Simona Brajkovic,1 Giulietta Riboldi,1 Dario Ronchi,1 Federica Rizzo,1 Nereo Bresolin,1,2 Stefania Corti,1 and Giacomo P. Comi1 Dino Ferrari Centre, Neuroscience Section, Department of […]

10-Jan-2014 - no open position at the moment

09-Jan-2014 - Sindem4Juniors

“What NEUROIMAGING AND BRAIN STIMULATION tell us on brain dysfunction in dementia” JANUARY 22-24, 2014 Cusanus Academy – Piazza Seminario 2, 39042 BRIXEN (BZ), ITALY […]

04-Nov-2013 - Offresi posizione come studente interno presso DEPT Sezione Neuroscienze UNIMI possibilità tesi

Offresi posizione come studente interno presso DEPT Sezione Neuroscienze UNIMI possibilità tesi Profilo: preferenzialmente studente UNIMI V anno medicina, valutabile altro profilo similare. Posizione: tirocinio […]

18-Oct-2013 - Cellular therapy to target neuroinflammation in amyotrophic lateral sclerosis

Federica Rizzo1, Giulietta Riboldi1, Sabrina Salani1, Monica Nizzardo1, Chiara Simone1, Stefania Corti1   and Eva Hedlund2   (1) Dino Ferrari Centre, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, Neurology Unit, IRCCS […]