Program

10.30 Welcome Notes and Update of the “International Research Staff Exchange Scheme (IRSES) – Marie Curie Actions – NO-MND” by Dr. Stefania Corti, PI of NO-MND and Program Coordinator, Milan University

10:45 “Introduction to MNDs” by Dr. Dimitra Papadimitriou, Co-Investigator of NO-MND, Biomedical Research Foundation Academy of Athens, Greece.

11:15 “A TSPO ligand improves motor performance and muscle innervation in a mouse model of amyotrophic laterals sclerosis“ by Dr. Diane Re, US Coordinator of the exchanges, Columbia University, New York, USA

11:45 “Axonal and synaptic genes with altered expression in human Spinal Muscular Atrophy motor neurons: molecular and therapeutic implications” by Dr. Federica Rizzo and Michela Taiana, Stefania Corti Laboratory, Milan University.

12:15 “Studying and modelling molecular mechanisms of neurodegeneration in Motor neuron diseases” by Dr. Paola Rinchetti, Stefania Corti Laboratory, Milan University.

12.40-13 Discussion

13-14.15 Lunch

14:15 “MiRNA profiling of ALS iPSCs and iPSC-derived motor neurons: molecular and therapeutic implication” by Dr. Mafalda Rizzuti and Dr. Valentina Melzi, Stefania Corti Laboratory, Milan University.

14:45 “Impaired mtDNA maintenance and neurodegeneration” by Dr. Dario Ronchi, Milan University

15:15 “ Mitochondrial dysfunction in iPSC-derived neurons of Multiple System Atrophy”, by Dr. Giacomo Monzio Compagnoni, Dr. Alessio Di Fonzo Laboratory, Milan University

15.45-16 Conclusive Remarks and Closing